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Orthobunyaviruses are linked to a broad spectrum of neurological disorders. However, the molecular determinants governing bunyavirus neuropathogenesis remain poorly understood, precluding the identification of drugs able to alleviate virus-induced neuronal dysfunctions. Here, we show that the prevalent, yet neglected,...
The results underscore Ayush-64's role in re-establishing immunometabolic balance and enhancing neural resilience, highlighting utilization of formulation against SARS-CoV-2 viral infection.
This chapter provides a comprehensive synthesis of microglial biology across multiple interfaces, including transcriptomic, lipid-associated metabolic, cell senescence, and metabolic reprogramming, and positions microglia biology as a metabolically plastic, spatially organized immune-regulated microenvironment that can...
This review highlights how neurotropic viruses co-opt epigenetic pathways to drive neurodegeneration and explores biomarker-driven strategies for personalized interventions in neurodegenerative disorders thus emphasizing potential epigenetic editing tools to restore neuronal homeostasis.
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