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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Yu-Xiao Ma

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#gene editing Oct 2026

Generation of DFNA5-deficient chickens reveals a species-specific role of pyroptosis in avian antiviral immunity

This work establishes the first germline-edited heterozygous DFNA5-mutant chicken model using primordial germ cell mediated genome editing and demonstrates that genetic disruption of DFNA5 markedly attenuates Raptinal-induced pyroptosis and reduces IL-1β and IL-18 secretion.

Jin-Gui Hao, Fei-Yi Wang, Man Xue et al. · 0 citations
Sep 2026

Age-associated chromatin repression of Hippo-Yap signaling drives oogonial stem cell decline in chicken

It is shown that OSC number and proliferative capacity decline significantly from pre-laying to late-laying stages, accompanied by increased follicular atresia, and epigenetic repression of the Hippo–YAP axis suppresses OSC proliferation through epigenetic repression of the Hippo–YAP axis.

Jia-Hui Wei, Jin Wang, Hong-Cai Sun et al. · 0 citations

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