Drug discovery requires continuous scientific decision-making across a vast research space. We introduce PharmAgents2, an autonomous system for end-to-end drug discovery that combines knowledge-enhanced decision-making with organized large-scale exploration. Paper2Skill extracts transferable scientific decision knowled...
Haichuan Tan, Bowen Gao, Tao Huang et al.· 0 citations
Current autonomous logical systems rely on a fragile assumption: that language models should dynamically write code, guess API payloads, and memorize operational constraints through prompt engineering. In practice, this burns massive context windows, inflates API bills, and produces brittle agents that fail unpredictab...
Many enterprise projects now pass free text to large language models (LLMs), and that text often contains personally identifiable information (PII) such as names, phone numbers, email addresses, home addresses and dates of birth. Once a prompt is sent, this data is copied into provider systems, application logs and obs...
Sai Yashwant, Manoj Kumar Gondimalla, Arjun Sharma et al.· 0 citations
Agent harness evolution enables recursive self-improvement (RSI) without updating model weights. We examine whether higher benchmark scores yield reliable, efficient, and transferable improvement. We evaluate four methods across harnesses, general and coding tasks. Repeated evaluations, controlled agent expansion, comp...
Xiaobo Wang, Zimu Wang, Siyu Ye et al.· 0 citations
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The domain of a fine-tune trained on a previously unseen dataset is recoverable well above chance from gray-box activations and black-box outputs, and activations and outputs were more informative than the weight-delta statistics.
The theoretical analysis clarifies the role of basis consistency and supports the proposed consistency-aware aggregation mechanism, FedAbA, which is proposed as a basis-consistent federated LoRA aggregation framework for heterogeneous ranks.
Peng-Peng Qiao, Yang Cao, Ling-Ling Zhang et al.· 0 citations
FlashOffloading is presented, a host-DRAM-centric inference architecture that fully offloads the KV cache in both the prefill and decode phases, optimizing KV offloading latency across the entire pipeline and delivering throughput gains under a time-per-output-token (TPOT) service-level objective (SLO).
Xuan Wang, Zhuan-Hao Wu, Ting-Zhu Fang et al.· 0 citations
CST-Bench is introduced, a benchmark for counterfactual spatial reasoning and CT-OPSD is proposed, which uses CST-Bench annotations to guide a teacher model in learning counterfactual state transitions and causal reasoning chains and provides an initial demonstration of how its annotations can support model improvement...
Goal-Branching is proposed, where blocking agents are given temporary goals, each tried as an additional branch of LaCAM's search, and random and corridor-aware rules for choosing these temporary goals are examined and it is shown that completeness is preserved for any such rule.
Stephen S. H. Chang, Daniel Damir Harabor· 0 citations
A rolling-horizon distributionally robust model that updates predictions of the remaining closure duration as observations of disruption resolution become available is developed, which minimizes the worst-case expected total completion delay over an ambiguity set of scenario probabilities.
Xiao-Bin Li, Yan-Bing Gao, Jia-Ning Long et al.· 0 citations
DelegateEval is proposed, a platform-level evaluation framework for agent systems that may combine large language models, reusable skills, protocols such as MCP, and executable tool environments and assess whether a platform enables people with different backgrounds to turn their expertise into ongoing services that de...
Ji-Chao Li, Jin-Rong Lu, Man-Jiang Yu et al.· 0 citations
This work formalizes LRM safety objectives as requiring non-malicious reasoning and answers, safety consistency, and explicit intent identification, and introduces a reasoning-preserving gradient projection mechanism that analytically resolves conflicts between safety and reasoning gradients, effectively eliminating th...
Yi-Chen Sun, Qi-Rui Liu, Yan Wang et al.· 0 citations