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protein folding

2,543 papers

#protein folding Dataset Open access Sep 2026

RolyPoly-tk Data Bundle: reference profiles and sequence sets for virus analyses

RolyPoly data bundle Date / Bundle Version: 2026-09-03 This deposit contains the custom built and reference (3rd party) data required for all functionality of RolyPoly-tk, an RNA-Virus analysis tool kit. This includes external raw databases, bundled for convinenve, and custom, purpose built datasets only released and t...

Uri Neri, Antônio Pedro Camargo, Dimitris Karapliafis · 0 citations
#protein folding Sep 2026

Two mitochondrial genomes and the phylogenetic relationships of Silpha (Coleoptera: Staphylinidae: Silphinae)

Silpha carinata (Herbst, 1783), and Silpha perforata (Gebler, 1832) (Coleoptera: Staphylinidae) belong to the tribe Silphini, which holds forensic significance due to its species’ rapid colonization of cadavers and relatively long developmental duration. In this study, we reported the complete mitochondrial genomes of...

Wei Zhen, Rui-Xin Zhang, Qi-Qi Lian et al. · 0 citations
#protein folding Sep 2026

Activity-guided native-PAGE electroelution coupled with DIA proteomics uncovers the superoxide dismutase and antioxidant network in mature peanut seeds.

An activity-guided workflow that combines native-PAGE NBT zymography, low-temperature dialysis-bag electroelution and DIA-based nano-LC-MS/MS to enrich native SOD complexes from seed crude extracts resolves the hidden antioxidant proteome of peanut seeds, providing a general strategy for studying isoenzyme repertoires...

Zi-Hao Wei, Feng Huang, Yu Wang et al. · 0 citations
#protein folding Sep 2026

Influence of sanguinarine on insulin amyloid fibrillogenesis: interaction, antifibrillation and defibrillation studies.

The findings from this study indicate that SNR possesses a significant inhibitory effect on HI fibrillation and finds that SNR possesses the ability to defibrillate the preformed fibrillar aggregates.

Shukdeb Sing, Arindam Das, Suraj Saha et al. · 0 citations
#protein folding Open access Sep 2026

44 Ferroptosis Suppressor Protein 1 (FSP1) Drives Ferroptosis Resistance in Chromophobe Renal Cell Carcinoma

The findings suggests that adaptation to ferroptotic stress may facilitate tumor progression in patients with higher FerrResistScores and in the TCGA-KICH cohort, patients with higher FerrResistScores exhibited reduced overall survival.

Steven Safi, Joelle Chami, Samer Salem et al. · 0 citations
#protein folding Open access Sep 2026

40 Ferritin-Dependent Iron Storage and Ferritinophagy Impact Ferroptosis Sensitivity in Chromophobe Renal Cell Carcinoma

This data indicates that ChRCC exhibits the second highest level of FTH1 expression relative to matched normal tissue in which FTH1 is 1.9-fold higher in ChRCC compared to normal kidney cells, suggesting impaired ferritin-derived iron mobilization.

Wafaa Bzeih, Tie-Gang Han, Michel Alchoueiry et al. · 0 citations
#protein folding Dataset Open access Sep 2026

Munich Crystallography BAG

The diverse groups of the Munich Crystallography BAG study a far range of subjects, reaching from structural aspects of fundamental cellular processes - such as RNA processing, protein folding and degradation, DNA repair, chromatin remodelling, enzymes - to the design of foldamers. The research groups are located at th...

Andreas Bracher, Vasilii Morozov · 0 citations
#protein folding Sep 2026

DNA aptamers to interfere with HasA, the hemophore of the heme assimilation system in Pseudomonas aeruginosa, as a potential antimicrobial strategy

Pseudomonas aeruginosa relies on heme acquisition to sustain growth and virulence in the iron-limited environment of the host, particularly in the acidic airways of patients with cystic fibrosis where antibiotic efficacy is markedly reduced. The Has heme assimilation system is initiated by the secreted hemophore HasA,...

Federico Bosetto, Tongyuan Wei, Katherine Stott et al. · 0 citations
#protein folding Open access Sep 2026

Females show less hypoxia-induced blood-brain barrier disruption in aged mice: a protective role for CD11c

Aging is associated with a decline in blood-brain barrier (BBB) integrity. Interestingly, recent reports suggest that females may be more resistant to BBB disruption than males. Using a robust model of hypoxia-induced BBB disruption, we exposed aged (20 months) male and female mice to chronic mild hypoxia (CMH; 8% O 2...

Arjun Sapkota, Sebok K. Halder, Alexis Garduno et al. · 0 citations
#protein folding Open access Sep 2026

Algorithmic Complexity Metrics for Biological Systems

This paper explores the development of novel algorithmic complexity metrics specifically tailored for analyzing the computational demands of biological systems, including protein folding, gene regulation, and cellular signaling pathways. Traditional complexity measures often lack the nuanced understanding required to e...

Jincheng Zhang · 0 citations
#protein folding Open access Sep 2026

Algorithmic Complexity Metrics for Biological Systems

This paper explores the development of novel algorithmic complexity metrics specifically tailored for analyzing the computational demands of biological systems, including protein folding, gene regulation, and cellular signaling pathways. Traditional complexity measures often lack the nuanced understanding required to e...

Jincheng Zhang · 0 citations
#protein folding Sep 2026

The role of ER-α36 and RUNX2 interaction in breast cancer progression.

The ER-α36 isoform is expressed in both ER-positive and ER-negative breast cancer cell lines. ER-α36 is implicated in promoting the proliferation, invasion, and metastasis of tumor cells. Runt-related transcription factor 2 (RUNX2) is widely recognized as a driver of bone-specific metastasis in breast cancer. The study...

Jia Sun, Xin Guan, Hongyan Li et al. · 0 citations

From tech blogs

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Google DeepMind Blog Sep 30, 2026

Introducing SynthID Bio

Proof of concept for watermarking AI-generated proteins while preserving biological function.

MIT News · Artificial Intelligence Aug 27, 2026

Looking beyond natural sequences

A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.

Google DeepMind Blog Nov 25, 2025

AlphaFold: Five years of impact

Explore how AlphaFold has accelerated science and fueled a global wave of biological discovery.

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