AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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2,623 papers
Quantum simulation holds immense promise for understanding and manipulating complex dynamical systems – phenomena ranging from fluid dynamics and climate modeling to protein folding and the behavior of complex chemical reactions. However, current simulation techniques face significant limitations, particularly when dea...
Interindividual variability in drug response arises from the complex interplay between inherited pharmacogenomic traits and environmental exposures. While genetic polymorphisms in cytochrome P450 (CYP450) enzymes are well-established determinants of metabolic capacity, the modulatory effects of environmental pollutants...
Interindividual variability in drug response arises from the complex interplay between inherited pharmacogenomic traits and environmental exposures. While genetic polymorphisms in cytochrome P450 (CYP450) enzymes are well-established determinants of metabolic capacity, the modulatory effects of environmental pollutants...
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This work presents a complete Ada/SPARK implementation of the V3 Architecture, a deterministic mechanical framework that unifies atomic structure and protein folding under a single physical substrate: phase pressure in the H₃O₂ condensate. The program demonstrates that two major scientific problems—the organization of...
Cardiovascular diseases account for a significant proportion of deaths worldwide. The common pathological feature underlying these diseases is atherosclerosis, which is characterized as an inflammatory condition driven by endothelial cell activation and dysfunction in its early stages. While the effects of the microbio...
The field of topology has witnessed significant advancements in understanding and manipulating complex network structures, from protein folding to genome sequencing. This research introduces a novel approach to topology optimization – the "Adaptive Topology Optimization Algorithm" – that leverages a self-adaptive topol...
Quantum error correction is a critical component of quantum computing, enabling the reliable operation of complex quantum algorithms. Current error correction schemes, however, are often cumbersome and require substantial overhead. This paper explores a novel quantum error correction scheme inspired by the self-correct...
Table S1. The list of Mettl14-dependent m6A peaks identified by m6A -SAC-seq. The table includes the chromosome, chromosomal position, original genome sequence, mutated sequence, mutation ratio among transcripts, gene symbol, and the genomic location of m6A peaks identified using m6A-SAC-seq by comparing P0 WT and M14...
Quantum error correction is a critical component of quantum computing, enabling the reliable operation of complex quantum algorithms. Current error correction schemes, however, are often cumbersome and require substantial overhead. This paper explores a novel quantum error correction scheme inspired by the self-correct...
Can the fundamental thermodynamic constraints of digestion and metabolic senescence be bypassed through pre-emptive molecular engineering? Under acute physiological exhaustion and severe nutrient starvation, standard enzymatic digestion collapses because breaking down tightly folded native globular proteins demands sub...
The structural basis for peptide prenylation by a ComQ-family enzyme is established, providing insight into the evolution of peptide-based indole prenylation within the IPPS superfamily, and support the view that ComQ-family enzymes constitute a distinct functional branch specialized for peptide modification.
Proof of concept for watermarking AI-generated proteins while preserving biological function.
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
Scientists are using AlphaFold to strengthen a photosynthesis enzyme for resilient, heat-tolerant crops.
Explore how AlphaFold has accelerated science and fueled a global wave of biological discovery.
AlphaFold has revealed the structure of a key protein behind heart disease
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