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DPF3a couples H3K36me2-dependent chromatin remodeling to genome architecture during myogenesis

Ming Yu Jingdong Xue Qi Zhang Yixuan Pan Min Hao Mingqian Hu Meiyang Liu Yuqiang Feng Yanhua Yao Mengyuan Peng Jun Wu Yu-Peng Chen Ping Hu Yi-Min Lao Bing Li
Aug 2026 · bioRxiv · 0 citations
Biology

TL;DR

The findings uncover a non-canonical mechanism whereby a chromatin remodeler regulates transcription primarily through three-dimensional genome organization rather than local accessibility control, and establish histone modification-guided chromatin remodeling as a key principle in gene regulation.

DOI Semantic Scholar
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