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Multiscale alterations and cortex-wide organizational trends in focal cortical dysplasia

E. Sahlas Judy Chen Arielle Dascal Benjamin Lévesque Kinder Charlotte Favre Yigu Zhou J. Royer Guido I. Guberman K. Xie J. Lam F. Fadaie R. Pana J. Hall T. Rüber A. G. Weil A. Bernasconi N. Bernasconi Boris C. Bernhardt
Jul 2026 · bioRxiv · 0 citations · 51 references
Biology

TL;DR

These findings provide robust evidence that multiscale MRI profiling can identify FCD signatures and contribute to in-vivo subtyping and the novel use of myeloarchitecture profiling and contextualization with macro-scale brain gradients provides new avenues to understand intracortical alterations and the embedding of FCD lesions into broader organizational patterns.

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