The findings support the hypothesis that neuropsychiatric symptoms could represent the early manifestation of Alzheimer's disease in older adults, and suggest depression and other neuropsychiatric symptoms may be predictors of AD's progression during its "preclinical" phase.
Objective: This review examines the relationship between depression and the development of Alzheimer’s disease (AD) in older adults, evaluating its impact on cognitive decline and neuropsychological functioning. The goal is to clarify the role of late-life and chronic depressive symptoms in the progression of AD, wit...
Bhumi N. Patel, E. Cesar· Archives of Clinical Neurops...· 0 citations
Dementia is a type of neurocognitive disorder (NCD) among others like delirium, amnesia, and other cognitive disorders due to traumatic brain injury,
substance/medication use, HIV infection, prion disease, Parkinson disease, Huntington’s disease, and other medical conditions. Patients usually present with
declining c...
Victoria Githenya· International Journal of Res...· 0 citations
Despite decades of intensive research, progress in treating late-onset Alzheimer's disease remains limited. A central problem may be conceptual: Alzheimer's disease may not be a single disease, but a heterogeneous syndrome arising from differing combinations of aging, genetic susceptibility, vascular injury, metabolic...
A. Korczyn· Journal of Alzheimer's Disea...· 0 citations
The theory that traumatic brain injury initiates Alzheimer's disease owes much of its existence to classical studies on boxers. It now appears that both the complexity of postmortem neuropathology and the clinical syndrome were not fully appreciated. Large scale studies linking epidemiology and biology continue to show...
R. Castellani· Journal of Alzheimer's Disea...· 0 citations
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