Mood disorders in late-life may be early warning signs for dementia

Anxiety: An early indicator of Alzheimer's disease?

The findings support the hypothesis that neuropsychiatric symptoms could represent the early manifestation of Alzheimer's disease in older adults, and suggest depression and other neuropsychiatric symptoms may be predictors of AD's progression during its "preclinical" phase.

Progression to Dementia in Very Late‐Onset Schizophrenia‐Like Psychosis Stratified by Alzheimer's Disease and Lewy Body Disease Biomarkers: A Retrospective Cohort Study

AD and/or LBD biomarker‐positive VLOSLP may be associated with greater dementia progression and cognitive decline, although findings should be interpreted cautiously given the small sample size and retrospective design.

Subjective cognitive impairment: Towards early identification of Alzheimer disease (cid:2)

Plasma GFAP modifies the association of depressive symptoms with cognitive function: A population‐based study

Late‐life depression is associated with cognitive impairment, but the underlying neural basis remains to be elucidated. We investigated the role of Alzheimer's disease (AD)–related plasma biomarkers in the depression–cognition association.

Post mortem MRI of cholinergic white matter pathways across neurodegenerative diseases

Cholinergic white matter pathway degeneration is central in Alzheimer's disease and Lewy body disease and can be assessed in vivo using magnetic resonance imaging proxies, but neuropathological validation is limited.

Dopaminergic‐ and Cholinergic‐Related Structural MRI Patterns Across Cognitive Subtypes of Parkinson's Disease With Mild Cognitive Impairment

The dual syndrome hypothesis distinguishes frontostriatal and posterior cortical cognitive subtypes in Parkinson's disease with mild cognitive impairment (PD‐MCI), which are associated with distinct cognitive profiles and different risks of dementia.