Oct 2026· IEEE Transactions on Pattern Analysis and Machine Intelligence· Vol PP· 0 citations
Computer ScienceMedicine
Abstract
Diffusion models (DMs) have steadily demonstrated outstanding performance in high-fidelity, controllable generation across diverse scenarios, following the "pretraining-finetuning" paradigm established in LLMs. Despite these advances, conventional DMs still face critical limitations in sophisticated reasoning, autonomous exploration of generation pathways, and adaptability to complex, human-aligned objectives. Inspired by RLHF's success in LLMs, RL has recently emerged as a pivotal post-training mechanism to iteratively refine DMs through reward-driven trajectory optimization. This paper presents the first comprehensive review of RL-driven DMs and empirical analysis of how RL reshapes the diffusion process towards experience-centric, goal-directed generation. We propose a novel technical panorama elucidating RL's multifaceted roles in diffusion-based language, multimodal, robotic, and scientific models-with granular focus on diffusion trajectory optimization and reward engineering. Through extensive experiments on multiple task-specific benchmarks, we systematically evaluate representative methods to intuitively highlight the advantages of different RL post-training strategies. Furthermore, we reveal and dissect three crucial bottlenecks that currently hinder the real-world deployment of RL-driven DMs: reward design fragility, exploration-exploitation trade-off in high-dimensional generation spaces, and training instability under sparse rewards. Based on these perspectives, we provide a principled roadmap for the integration of RL into DMs and outline promising future research directions for robust, interpretable RL-diffusion systems. We also construct a public repository to continuously track the latest developments in this rapidly evolving field: https://github.com/lyongo/Awesome-RL-for-Diffusion-Models.
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