Jul 2026· Adolescência e Saúde· Vol 21, pp. 259-264· 0 citations· 37 references
TL;DR
The current literature review aims to survey the variety and extension of SC-application in tissue-regenerative dentistry.
Abstract
Regenerative medicine is the branch of medicine that aims to repair and regenerate damaged tissues and presents promising avenues for addressing a wide range of currently incurable diseases. Regenerative medicine is based on the use of cell therapy with stem cells that can differentiate into differentiated cells of specific tissues. There are various types of stem cells, which are different in potential and derivation.
The donor cells and immune cells play a prominent role in determining the clinical success of MSCs therapy. In line with the promising future that stem cell therapy has shown for tissue engineering applications, dental stem cells have also attracted the attention of the relevant researchers in recent years. The current literature review aims to survey the variety and extension of SC-application in tissue-regenerative dentistry.
Although further study is needed to support the clinical application of i-dMSCs, these results indicate that they have the potential to become the seed cell for stem cell therapy, providing new ideas for the field of regenerative medicine.
The molecular mechanism of stem cell-mediated dental tissue repair is clarified to clarify the molecular mechanism of clinical transformation prospects, provide experimental basis for clinical translational research, and promote the development of personalized dental tissue regeneration strategies.
Jin-Tong Lv· International Journal of Pub...· 0 citations
An overview of how nanomaterials regulate stem cell biological functions and activate associated signaling pathways is provided, followed by a discussion of future directions and challenges in this field.
Xue-Tong Wang, Yi-Ming Sun, Ping Zhang et al.· Cytotherapy and Longevity· 0 citations
The effects that engineering of the niche by 3D bioreactor, xenogeneic-free media, and genetic manipulation of cells have on clinical outcomes in the context of stem cell therapies for neurological, cardiovascular, orthopedic, and immunological purposes are addressed.
Ryan Jianwen Deng· Theoretical and Natural Scie...· 0 citations
Current evidence supports the safety of regenerative therapies; however, their efficacy varies according to the underlying condition and clinical context, and multi-modal approaches combining cells, growth factors, and scaffolds appear to outperform monotherapies.
Joahnni Raúl Clark Rivera Padilla, Luis Fernández de Córdova Río de la Loza, Arnulfo Erick de la Paz Martínez· International Journal of Med...· 0 citations
Fundamental research on GMSC-based therapies has elucidated the multiple immunomodulatory and regenerative pathways employed by these cells to achieve therapeutic effects, underscoring their substantial potential across both chronic inflammation and regenerative medicine applications.
Xinran Tong, Xin Yu, Shan Wang et al.· Molecular Biology Reports· 0 citations
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