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2,452 papers
CCL17 is a novel potential biomarker for PU pathogenesis and prognosis and demonstrated high clinical relevance in the patients with PU.
BACKGROUND Walnut meal, a major by-product of oil extraction, is rich in protein and bioactive compounds but suffers from poor palatability and low digestibility due to anti-nutritional factors (ANFs) such as phytic acid, tannins, and trypsin inhibitors. Conventional processing methods fail to address these limitations...
There was a positive correlation between TLR-2 expression and inflammatory and disease activity indicators, and TLR-2 expression was considerably higher in RA patients, suggesting that TLR-2 might be a useful biomarker for RA activity and development.
Start with the six-page PDF. On 19 September 2026 Edison Scientific and FutureHouse published twelve Millennium Problems for Biology with explicit acceptance criteria. This note takes two of them, Problem 3 (the reverse translatase) and Problem 10 (the protein amplification chain reaction), and proves what the criteria...
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AlphaFold 3 (AF3) has transformed structural bioinformatics through generative diffusion modeling of biomolecular assemblies. However, intrinsically disordered regions (IDRs)—which comprise over 30% of the human proteome and mediate essential cell signaling, oncogenesis, and phase separation—violate the classic thermod...
Genetically proxied smoking was associated with increased risks of uIAs and aSAH, and smoking-related proteins with the risk of unruptured intracranial aneurysms and aneurysmal subarachnoid hemorrhage were assessed.
Geranium (Pelargonium graveolens L.) is an important aromatic plant valued for its essential oil; however, its cultivation in sandy soils is often constrained by poor fertility and limited water-holding capacity. Therefore, this study was conducted to evaluate the effects of Azolla and Moringa extracts on growth, essen...
A variety of insect pests pose a serious threat to global cotton production. Among these, pink bollworm (PBW) and whiteflies are the most devastating, resulting in substantial yield losses and increased pesticide use. Conventional insect-resistance strategies, which primarily rely on single Bacillus thuringiensis (Bt)...
Coarse RNA coordinate representations are widely used, yet the biological information they encode remains unquantified. We introduce FORGE, which converts a seven-atom RNA geometry representation into 935 interpretable descriptors and reports which residue-level annotations this geometry supports. On 4,135 post-2025 RN...
This study establishes the feasibility of dCasRx-mediated programmable RNA base editing in plant cells and lays a foundation for further optimization of editing efficiency and stable in planta editing performance.
This ex vivo primary ferret nasal epithelial cell and peripheral blood mononuclear cell co-culture model shows that signaling decoupling across the "epithelial-immune bridge" drives suboptimal IBV immunogenicity.
This first study to include Olink Reveal in a systematic cross-platform comparison and to directly compare the Orbitrap Astral with the previous-generation Orbitrap Exploris 480 under identical conditions provides a concrete, evidence-based framework for workflow selection and support the co-deployment of deep MS and h...
Proof of concept for watermarking AI-generated proteins while preserving biological function.
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
Scientists are using AlphaFold to strengthen a photosynthesis enzyme for resilient, heat-tolerant crops.
Explore how AlphaFold has accelerated science and fueled a global wave of biological discovery.
AlphaFold has revealed the structure of a key protein behind heart disease
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