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2,530 papers
Clinical necessity for an optimized post-thaw acclimation incubation period prior to cell administration is highlighted, highlighting the clinical necessity for an optimized post-thaw acclimation incubation period prior to cell administration.
Touchstone alpha v1.0 What it is Four HTML files that open in any browser, offline, sending nothing anywhere. Plus two Python twins of the same engines for terminal or Colab work. Copyright © 2026 David Coates, MIT. A touchstone is a piece of dark stone: rub gold against it and the streak tells you what the metal reall...
Microfluidic chips are promising for on-site analysis in medical diagnostics and food safety because they enable miniaturized, integrated sample processing. However, the analysis of complex, salt-rich matrices of biological and food samples remain challenging for conventional closed chips and electrokinetic pretreatm...
Abstract: This study presents a testable quantum-informational and biophysical framework to resolve two of the most fundamental crises in theoretical physics and observational cosmology: the Cosmological Constant Catastrophe ($10^{120}$ discrepancy) and the late-time cosmic acceleration transition ($z \approx 0.5$). Mo...
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Abstract: This study presents a testable quantum-informational and biophysical framework to resolve two of the most fundamental crises in theoretical physics and observational cosmology: the Cosmological Constant Catastrophe ($10^{120}$ discrepancy) and the late-time cosmic acceleration transition ($z \approx 0.5$). Mo...
This dataset contains the AlphaFold2, AlphaFold3 and integrative structural models, together with native mass spectrometry and mass photometry data, underlying Haas et al., “Integrative structure of norovirus NS3 suggests a role in RNA transport”. Norovirus NS3 is a membrane-bound AAA+ ATPase of superfamily 3 (SF3). Th...
This dataset contains the AlphaFold2, AlphaFold3 and integrative structural models, together with native mass spectrometry and mass photometry data, underlying Haas et al., “Integrative structure of norovirus NS3 suggests a role in RNA transport”. Norovirus NS3 is a membrane-bound AAA+ ATPase of superfamily 3 (SF3). Th...
Findings support a conserved capacity of selected classical adhesins to serve as candidate docking partners for exogenous Gpm1 and demonstrate the ability of surface-associated Gpm1 to interact with the host contact system components across pathogenic yeasts.
A surface display strategy is utilized to construct an adhesion‐enhanced Escherichia coli Nissle 1917 chassis that effectively alleviates inflammation, restores epithelial barrier integrity, and reverses oxidative damage in both prophylactic and therapeutic murine colitis models.
Extracellular vesicles (EVs) mediate intercellular transfer of lipids, proteins, and nucleic acids between cell types. We previously showed that astrocyte‐derived EVs modulate neuronal mitochondria in vitro. Whether endogenous astrocytic EVs associate with neuronal mitochondria in vivo remained unknown. To address this...
A 125-plex Sb secretion construct library was developed consisting of all possible combinations of five promoters, five secretion signals, and five terminators, which enabled a greater than 1800-fold range in Sb expression of a Gaussia luciferase (GLuc) reporter.
Findings establish a mechanistic relationship between hydrophobic interaction-driven complexation, protein conformational remodeling, and delivery performance, highlighting β-lactoglobulin as a promising protein-based carrier for improving the delivery of bioactive compounds.
Proof of concept for watermarking AI-generated proteins while preserving biological function.
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
Scientists are using AlphaFold to strengthen a photosynthesis enzyme for resilient, heat-tolerant crops.
Explore how AlphaFold has accelerated science and fueled a global wave of biological discovery.
AlphaFold has revealed the structure of a key protein behind heart disease
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