A plasmid-based reverse genetics system was established for red-spotted grouper nervous necrosis virus, and codon mutations on B1 and B2 proteins were introduced, and all mutated codons had been reverted to the original sequence.
Yu-Qi Zhang, Xiao-Qian Tang, Xiu-Zhen Sheng et al.· Fish and Shellfish Immunolog...· 0 citations
It is shown that pIgR-targeted bispecific antibodies rapidly deplete from serum, while enriching 5-10-fold in bronchoalveolar lavage fluid compared to normal IgG antibodies, which support the use of anti-pIgR bispecific antibodies to treat diseases requiring targeting in mucosal areas.
Kelsie Marks, Nirav Shah, L. Phạm et al.· mAbs· 0 citations
Preliminary evidence is provided for establishing an efficient transient expression platform while offering initial mechanistic insights into how iron ions influence PEI-mediated transfection via complex morphology and transcriptional regulation.
Yu Liu, S. Xiao, Yu-Qian Gui et al.· Biochemistry and Biophysics...· 0 citations
Selectin plays a crucial role in the form of a key molecular mediators for feto-maternal communication during pregnancy. Particularly, P-selectin is an adhesion molecule expressed predominantly on activated endothelial cells and platelets is also widely recognized for its role in leukocyte recruitment during inflammati...
Anshuman Kumar, I D Gupta, S K Niranjan et al.· Zenodo (CERN European Organi...· 0 citations
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Transportation exposes sheep to physical, physiological, and psychological stressors—such as loading, vehicle movement, confinement, social mixing, feed/water deprivation, and thermal extremes. These factors disrupt homeostasis, triggering the sympathetic–adrenomedullary system and the hypothalamic–pituitary–adrenal ax...
S S Dangi, V Ralte, S K Dangi et al.· Zenodo (CERN European Organi...· 0 citations
Transportation exposes sheep to physical, physiological, and psychological stressors—such as loading, vehicle movement, confinement, social mixing, feed/water deprivation, and thermal extremes. These factors disrupt homeostasis, triggering the sympathetic–adrenomedullary system and the hypothalamic–pituitary–adrenal ax...
S S Dangi, V Ralte, S K Dangi et al.· Zenodo (CERN European Organi...· 0 citations
Selectin plays a crucial role in the form of a key molecular mediators for feto-maternal communication during pregnancy. Particularly, P-selectin is an adhesion molecule expressed predominantly on activated endothelial cells and platelets is also widely recognized for its role in leukocyte recruitment during inflammati...
Anshuman Kumar, I D Gupta, S K Niranjan et al.· Zenodo (CERN European Organi...· 0 citations
INTRODUCTION: Bovine (Bos taurus and Bos indicus) and buffalo (Bubalus bubalis) are economically important livestock species and major contributors to milk and meat production. Assisted reproductive technologies, particularly in vitro embryo production (IVEP), provide important opportunities for the rapid multiplicatio...
V S Chouhan, Anindita Senapati, Ravinder et al.· Zenodo (CERN European Organi...· 0 citations
INTRODUCTION: Bovine (Bos taurus and Bos indicus) and buffalo (Bubalus bubalis) are economically important livestock species and major contributors to milk and meat production. Assisted reproductive technologies, particularly in vitro embryo production (IVEP), provide important opportunities for the rapid multiplicatio...
V S Chouhan, Anindita Senapati, Ravinder et al.· Zenodo (CERN European Organi...· 0 citations
In goats, apocrine milk secretion sheds cytoplasmic particles and epithelial cells into milk as a normal physiological event, so uninfected udders sustain higher somatic cell counts (SCC). To characterise the immunophysiology underlying rising SCC and test whether it reaches a fermented product, forty-eight healthy ear...
In goats, apocrine milk secretion sheds cytoplasmic particles and epithelial cells into milk as a normal physiological event, so uninfected udders sustain higher somatic cell counts (SCC). To characterise the immunophysiology underlying rising SCC and test whether it reaches a fermented product, forty-eight healthy ear...
Antimicrobial resistance (AMR) is one of the most pressing current global health challenges, threatening human and animal health, food security, and environmental sustainability. The extensive use and misuse of antibiotics in human medicine and livestock production system have accelerated the emergence of multidrug-res...
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
