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Open access Jul 2026

Design of a bioactive nickel(II) complex based on a hydrazone Schiff base ligand: Synthesis, structural characterization and antimicrobial investigations

The nickel complex exhibited significantly enhanced antibacterial activity compared to the free ligand, an improvement that may be attributed to the chelation effect and the increased lipophilicity of the complex.

M. Dieng, A. Sall, M. Faye et al. · 0 citations
Open access Aug 2026

Synthesis, characterization, antimicrobial, antibiofilm, and molecular docking studies of Cu(II) and Zn(II) Schiff base complexes derived from L-tyrosine and indole-3-carboxaldehyde

These synthesized Schiff base complexes efficiently disrupted biofilms, providing a promising approach for managing chronic infections associated with resistant bacteria.

Aparna Mohan, A. Joy, P. Rajan et al. · 0 citations
Open access Aug 2026

Synthesis, structural elucidation, antimicrobial performance, and DNA-binding behavior of a new N2O2 tetradentate schiff base and its transition metal and uranyl complexes

A new tetradentate N2O2 Schiff base ligand derived from 2,6-diaminopyridine and 2,4-dihydroxybenzaldehyde was synthesized and used to prepare its Cu(II), Co(II), Ni(II), Mn(II), and UO2 (II) complexes. The ligand and complexes were fully characterized by elemental analysis, FT-IR, UV–Vis, 1H/13C NMR, ESR, mass spectrom...

Reham H. Wahba, M. A. Diab, E. A. Gomaa et al. · 0 citations
Open access Jul 2026

Green synthesis of tetrahydropyridine-3-carboxylate derivatives and evaluation of antimicrobial and antimalarial activities supported by molecular docking, POM studies, and drug-likeness analysis

Findings highlight haloarene-decorated tetrahydropyridine derivatives as promising dual-action candidates with potential to combat both bacterial and malarial infections.

Bhavesh S. Hirani, Mohammad Murwih Alidmat, L. Hasoun et al. · 0 citations
Jul 2026

Synthesis, antibacterial, and antibiofilm activities of an adenosine-benzoic acid conjugate against Streptococcus mutans and Escherichia coli: insights from molecular docking.

Molecular docking results provided a molecular basis for the conjugate's interaction with target proteins (PDB IDs: 4LFU and 4TQX), suggesting its potential as a quorum-sensing modulator.

Nadia Fattahi, Nazia Tabassum, Fazlurrahman Khan et al. · 0 citations
Open access Jul 2026

Pharmacological potential of the marine peptide cyclo(L-phenylalanyl-L-prolyl) against both multidrug-resistant, gram-negative Acinetobacter baumannii and gram-positive Staphylococcus aureus: structure – activity relationship, computational and experimental studies

The experimental and computational findings suggest that cFP is a promising antimicrobial lead and warrant further mechanistic and translational investigation.

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