Abstract Dentin is the primary mineralized tissue of the tooth, essential for pulp protection and enamel support. Its regenerative capacity is critical for dental health. This review summarizes recent progress in odontogenic regeneration, covering fundamental biological mechanisms and translational applications. A lite...
Yan-Tong Wang, Deng-Sheng Xia, Jing-Wen Wu et al.· ACS Applied Bio Materials· 0 citations
Regeneration encompasses a variety of processes across biological, urban, and technological domains. This chapter explores the theories, types, and future prospects of regeneration, emphasizing physiological regeneration, urban regeneration through smart technologies, and the potential of regenerative medicine. By synt...
Bacterial antimicrobial resistance (AMR) represents a global public health crisis that threatens to render conventional antibiotic regimens obsolete. The clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR/Cas9) system has emerged as a revolutionary tool in molecular biology, offering...
SUGP1 (SURP and G-patch domain containing 1) participates in splice-site recognition through its interaction with SF3B1, and loss of this factor leads to aberrant splicing. While its role in pre-mRNA splicing is well-documented, its impact on small RNA pathways remains poorly understood. Here, we used CRISPR/Cas9-media...
Dan Liu, Yongkang Guo, Liting Wang et al.· Biology· 0 citations
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Phosphorus (P) is a crucial plant macronutrient, but the non-renewable nature of P sources for plant growth in soils globally limits crop productivity, causing great concern for future sustainable agriculture and global food security. Thus, improving plant phosphorus use efficiency (PUE) by increasing P-utilization and...
Lalchand, Rajesh Ramasandra Venkataraja, Pramod Kumar Meghwal et al.· Frontiers in Plant Science· 0 citations
ABSTRACT Accurate and scalable evaluation of gene‐editing efficiency is crucial for the development of novel editing tools. However, conventional methods are laborious, costly, and low‐throughput. Here, we developed an artificial intelligence (AI)‐driven fluorescent reporter (AR) platform, an integrated system that aut...
Mingming Xue, Hanhan Li, Yuwan Zheng et al.· Animal Research and One Heal...· 0 citations
CD36 (Cluster of Differentiation 36) is a transmembrane glycoprotein that plays a crucial role in various cellular processes, and has been implicated in cancer progression, metastasis, chemoresistance, and radio-resistance. CD36 has recently gained attention as a potential therapeutic target in cancer treatment. CRISPR...
M.W.S. Perera· Sabaragamuwa University Jour...· 0 citations
We examined how religious and spiritual beliefs and practices impact attitudes toward genomic medicine among individuals from six major U.S. religious groups: Black Protestant, Evangelical Protestant, Mainline Protestant, Catholic, Jewish, and Muslim. We surveyed U.S. adults (N = 4939) assessing their religious affilia...
Erin D. Solomon, Eu Gene Chin, James M. DuBois· Digital Commons@Becker (Wash...· 0 citations
Background: Amelogenesis imperfecta (AI) has recently been realized as not only an inherited enamel anomaly, but also a genetically heterogeneous developmental disorder and a compelling model for the study of enamel biomineralization and craniofacial development. Methods: This review is a narrative synthesis of the sta...
Zein-based gene delivery remains preclinical and requires stronger mechanistic, cargo-specific and route-specific validation, and translational rationale for zein lies not in superior intrinsic transfection efficiency, but in route-specific protection, sustained release, hydrophobic drug co-loading and use as a biodegr...
Dua Alsinglawi, Enass Serry Moursy, Bilgesu Kasurka et al.· International Journal of Bio...· 0 citations
This review summarizes the development of plant base editors, computational tools for target design, and their applications in crop research, and examines editor architectures and compares editing efficiency, product purity, and specificity, with particular attention to transversion editing.
Ning Sui, Jie-Kun Zhang, Wen-Yue Xu et al.· Biotechnology Advances· 0 citations
In the future, integration of protein regulation, gene editing technologies, and precision therapeutic approaches may enable specific targeting of LD-mitochondria communication, thereby offering new avenues for the treatment of relevant diseases.
Yang Ding, Xiao-Hong Xie, Yang-Kun Li et al.· Pharmacological Research· 0 citations
Zero-knowledge proofs can verify computing results without rerunning workloads or exposing sensitive data. Magnetar helps bring them into the mainstream with support for standard programming languages, major speed gains, and quantum-resistant security. The post Proof-based general-purpose computing with Magnetar appeared first on Microsoft Research.
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.
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