This study describes the development and application of a wheat-compatible prime-editing system to introduce the Lr67-associated TaSTP13(G144R) resistance allele into the A, B, and D TaSTP13 homoeologs of hexaploid wheat. Edited lines were generated and characterized for editing efficiency, followed by evaluation of le...
Rafael E. Venado, Joshua Waites, Easter D. Syombua et al.· Figshare· 0 citations
The genus Sorbus sensu lato (Maleae, Rosaceae) represents one of the most taxonomically complex groups in Rosaceae due to extensive hybridization, polyploidization, and morphological convergence. Although East Asia represents a major center of diversity for Sorbus s.l., the organellar genomes of East Asian simple-leave...
Xiong Li, Yu Feng, Chengwu Liu et al.· BMC Plant Biology· 0 citations
Cancer immunotherapy is a transformative technology allowing for the elimination of malignant cells through immune system stimulation; however, the large-scale clinical application of adoptive cellular therapy technologies is limited due to difficulties in ex vivo immune cell engineering, high costs, and complicated ma...
Hari Krishnareddy Rachamala, Sandeep Atla, R. S. Angom· Frontiers in Pharmacology· 0 citations
This study describes the development and application of a wheat-compatible prime-editing system to introduce the Lr67-associated TaSTP13(G144R) resistance allele into the A, B, and D TaSTP13 homoeologs of hexaploid wheat. Edited lines were generated and characterized for editing efficiency, followed by evaluation of le...
Rafael E. Venado, Joshua Waites, Easter D. Syombua et al.· Figshare· 0 citations
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Micronutrient deficiencies, particularly of iron (Fe) and zinc (Zn), are major global health concerns for humans, especially in populations that rely heavily on cereal-based diets. Rice grains, one of the world’s most consumed staple crops, have low concentrations of bioavailable Fe and Zn, especially in the endosperm...
P. K. Menguer, Lucas Adamy Lenhardt, Marcos Bönes et al.· Frontiers in Plant Science· 0 citations
Common buckwheat (Fagopyrum esculentum) is a climate-resilient pseudocereal; however, its global adoption is constrained by the heteromorphic self-incompatibility associated with distyly. While the S-locus early flowering 3 (FeS-ELF3) gene has been identified as a key regulator of self-compatibility, a stable genetic t...
Artur Piński, Magdalena Zaranek, Joanna Lusinska et al.· Frontiers in Plant Science· 0 citations
Origanum vulgare is a perennial herb known for its antimicrobial, antioxidant, and anti-inflammatory properties, valued in both traditional medicine and modern phytopharmacology. Despite substantial research on its chemical and pharmacological properties, genomic studies have been limited. In this study, we present the...
Curated dataset and analysis code for a deduplicated census of the mobilized colistin resistance (mcr) gene family in the August 2026 NCBI snapshot (AMRFinderPlus Reference Gene Catalog 2026-08-07.1). Contents. Four archives: (1) core curated datasets (1,298 → 1,106 records, 454 unique proteins, 284-protein QC-triage c...
Shilei Dong· Zenodo (CERN European Organi...· 0 citations
Curated dataset and analysis code for a deduplicated census of the mobilized colistin resistance (mcr) gene family in the August 2026 NCBI snapshot (AMRFinderPlus Reference Gene Catalog 2026-08-07.1). Contents. Four archives: (1) core curated datasets (1,298 → 1,106 records, 454 unique proteins, 284-protein QC-triage c...
Shilei Dong· Zenodo (CERN European Organi...· 0 citations
This comprehensive foundational module analyzes the systems architecture and developmental mechanics of emerging technologies across the modern STEM curriculum. Developed by Prep4Uni.Online, this resource serves as an analytical bridge connecting laboratory-stage scientific discovery to scalable industrial engineering...
Prep4Uni.Online· Zenodo (CERN European Organi...· 0 citations
This archive supports the manuscript "Mitoxyperilysis-consistent L4 de-protection in human sepsis-associated ARDS blood: a compartment- and etiology-bounded transcriptomic boundary map" (submission target: Critical Care, BMC; manuscript version v2.34, September 2026). Contents: (1) complete analysis code (R 4.6.1 / Pyt...
linhuangwei, Yuanshui Liu· Zenodo (CERN European Organi...· 0 citations
CRISPR–Cas9 genome editing has transformed biomedical research by enabling precise and efficient genetic modification. Among its applications, gene knockout using ribonucleoprotein (RNP) complexes provides a non-viral strategy for introducing loss-of-function mutations. Here, we present an optimized CRISPR–Cas9 RNP-bas...
Andrea Šarac, Klemen Kunej, Kristina Manzoni et al.· Scientific Reports· 0 citations
Zero-knowledge proofs can verify computing results without rerunning workloads or exposing sensitive data. Magnetar helps bring them into the mainstream with support for standard programming languages, major speed gains, and quantum-resistant security. The post Proof-based general-purpose computing with Magnetar appeared first on Microsoft Research.
