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gene editing

1,701 papers

#gene editing Review Open access Sep 2026

Epigenetic strategies for mitigating kidney fibrosis

Renal fibrosis is the irreversible pathological core of chronic kidney disease (CKD). Current treatments can slow disease progression, but cannot cure it. Epigenetic regulatory mechanisms provide new perspectives for understanding and intervening in this process. This review summarizes the core epigenetic regulatory ne...

Cong Wang, Yun-Tong Wu, Li-Juan Yu · 0 citations
#gene editing Review Open access Sep 2026

Top advances of the year in autologous cellular therapy in melanoma and solid tumors

The year 2025 marked significant advances in autologous cellular therapy for melanoma and solid tumors, building on landmark regulatory approvals in 2024. Lifileucel, the first Food and Drug Administration‐approved tumor‐infiltrating lymphocyte (TIL) therapy for advanced melanoma, demonstrated durable efficacy in the 5...

Kimberly Loo, A. Betof · 0 citations
#gene editing Open access Sep 2026

Affordability over perceived safety: Consumer acceptance of emerging insulin production technologies

Consumer acceptance of insulin produced via a gene-edited production system compared with insulin produced using conventional genetically modified microbial methods is examined to suggest that affordability plays a more influential role than perceived safety in shaping consumer acceptance of emerging biotechnology-base...

Nathan P. Kemper, B. McFadden · 0 citations
#gene editing Open access Sep 2026

A CS•CBE System Targeting β‑Catenin: Exploring Additional Inhibition Targets for Colon Cancer Proliferation

A CS•CBE integrative delivery and editing system via chitosan and cytosine base editor (CBE), which could successfully target and inhibit the phosphorylation of β-catenin, serves as a valuable research tool for targeted protein modulation, downstream target identification, and probe specific post-translational modifica...

Min Li, Qian Ban, Da-Hai Liu et al. · 0 citations
#gene editing Open access Sep 2026

FigureLab: a browser-based tool for assembling publication-quality scientific figures

FigureLab is a single-file, browser-based application for assembling publication-quality scientific figures from image data (microscopy, western blots, histology, gels, and clinical or specimen photographs). It runs entirely client-side with no installation, server, or internet connection required, so no image data eve...

Michael Baffour Awuah · 0 citations
#gene editing Review Open access Sep 2026

Engineering strategies to address immune and delivery barriers in pancreatic ductal adenocarcinoma: a barrier-matched translational framework

This review evaluates oncolytic virotherapy, gene-editing technologies, engineered immune-cell therapies, nanotechnology-enabled delivery systems, and artificial intelligence-assisted precision oncology according to the PDAC barriers they are intended to address and the maturity of the supporting evidence.

Yang Li, Yu Li, Jia Fan et al. · 0 citations
#gene editing Open access Sep 2026

Comparative plastid genomics reveals phylogenetic relationships and candidate molecular markers in Salvia

The plastid genomes of Salvia are structurally conservative but contain sufficient localized variation for marker development and species discrimination, and the expanded plastome phylogeny improves resolution of major evolutionary lineages within the genus.

Cheng-Wen Gao, Yu-Jie He, Ming-Xuan Wu · 0 citations
#gene editing Open access Sep 2026

Comparative chloroplast genomics in Amorphophallus: revealing codon usage patterns and phylogenetic clades across 16 species

Amorphophallus is an important genus within Araceae, possessing economic value and considerable ornamental diversity. However, accurate taxonomic identification using traditional methods remains challenging due to pronounced morphological plasticity and the temporal separation of leaf and flower emergence. To date, lar...

Haoliang Shi, Qinghu Lu, Ying Qi et al. · 0 citations
#gene editing Review Open access Sep 2026

HIV cure: from early therapies to cutting-edge strategies

HIV has challenged humanity for decades, quietly establishing latent reservoirs that evade even the most potent antiretroviral therapies (ART). While ART transformed HIV from a fatal disease into a manageable condition, the virus’s hidden persistence continues to fuel the global epidemic. This review narrates the story...

Z. Safaei, K. Khalili · 0 citations
#gene editing Open access Sep 2026

CRISPR-Based Therapeutic Approaches in Lung Cancer

This research paper explores the potential of CRISPR-based therapeutic approaches in the diagnosis, treatment, and management of lung cancer. It examines how CRISPR-Cas genome-editing technologies can be used to identify and modify cancer-associated genes, investigate molecular mechanisms of tumor development, and deve...

Zeeshan Qaiser · 0 citations
#gene editing Book Open access Sep 2026

Book for Genetic engineering by Prof. Dr. Zeeshan Qaiser

Genetic Engineering: Principles, Technologies, Genomics, Genome Editing and Translational ApplicationsThis book provides a comprehensive and contemporary overview of genetic engineering, covering its fundamental principles, molecular technologies, genomic applications, genome editing approaches, and emerging translatio...

Zeeshan Qaiser · 0 citations
#gene editing Review Open access Sep 2026

Advances in Sexual and Asexual Propagation of Toxicodendron vernicifluum: Mechanisms, Bottlenecks, and Industrialized Breeding Perspectives

Toxicodendron vernicifluum is an economically important lacquer-producing tree endemic to East Asia; propagation bottlenecks severely restrict elite clone industrialization. This review summarizes 20 years of the domestic and international literature on seed propagation, root cutting, stem cutting, grafting, and tissue...

Xue-Hui Tian, Qing-Ning Wang, Xuan-Feng Cao · 0 citations

From tech blogs

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Microsoft Research Blog Oct 15, 2026

Proof-based general-purpose computing with Magnetar

Zero-knowledge proofs can verify computing results without rerunning workloads or exposing sensitive data. Magnetar helps bring them into the mainstream with support for standard programming languages, major speed gains, and quantum-resistant security. The post Proof-based general-purpose computing with Magnetar appeared first on Microsoft Research.

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