Geranium (Pelargonium graveolens L.) is an important aromatic plant valued for its essential oil; however, its cultivation in sandy soils is often constrained by poor fertility and limited water-holding capacity. Therefore, this study was conducted to evaluate the effects of Azolla and Moringa extracts on growth, essen...
Hala S. Abd-Rabbu, F. Aboud, K. Khalid· BMC Plant Biology· 0 citations
A variety of insect pests pose a serious threat to global cotton production. Among these, pink bollworm (PBW) and whiteflies are the most devastating, resulting in substantial yield losses and increased pesticide use. Conventional insect-resistance strategies, which primarily rely on single Bacillus thuringiensis (Bt)...
Saira Azam, Aftab Ahmad, Ayesha Latif et al.· Journal of Cotton Research· 0 citations
Coarse RNA coordinate representations are widely used, yet the biological information they encode remains unquantified. We introduce FORGE, which converts a seven-atom RNA geometry representation into 935 interpretable descriptors and reports which residue-level annotations this geometry supports. On 4,135 post-2025 RN...
Leighton Gow, Jintang Li, Xianhan Tan et al.· bioRxiv· 0 citations
This study establishes the feasibility of dCasRx-mediated programmable RNA base editing in plant cells and lays a foundation for further optimization of editing efficiency and stable in planta editing performance.
Xue-Ming Ruan, Zi-Yan Zhang, Xiang-Yu Xiong et al.· Biochemical and Biophysical...· 0 citations
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This ex vivo primary ferret nasal epithelial cell and peripheral blood mononuclear cell co-culture model shows that signaling decoupling across the "epithelial-immune bridge" drives suboptimal IBV immunogenicity.
This first study to include Olink Reveal in a systematic cross-platform comparison and to directly compare the Orbitrap Astral with the previous-generation Orbitrap Exploris 480 under identical conditions provides a concrete, evidence-based framework for workflow selection and support the co-deployment of deep MS and h...
Jean-Marc Monneuse, Hayat Hage, Célie Da Silva et al.· Journal of Proteomics· 0 citations
Results demonstrated that ProtThermoRank provides a sequence-based approach for artificial intelligence-guided protein engineering, enabling in-silico high-throughput screening of thermostabilizing variants and accelerating the discovery and optimization of highly stabilizing proteins.
Sungbo Hwang, Sohee Oh, Jin-Sik Kim et al.· International Journal of Bio...· 0 citations
The results demonstrate the promising potential of PCV2 VLPs as versatile epitope-display platforms, while establishing the IDR as a suitable fusion site that maintains both structural integrity and biological functionality.
Hong Li, Xiao-Ming Huang, Yu-Xin Zhao et al.· International Journal of Bio...· 0 citations
Osteogenesis imperfecta (OI) is a genetically heterogeneous connective tissue disorder characterized by bone fragility, recurrent fractures, skeletal deformities, and substantial variability in clinical severity. Although OI is primarily associated with defects in type I collagen or proteins involved in its processing,...
Zhiming Wu, Regenerative Medicine and Stem Cells, ORT Research et al.· Utrecht University Repositor...· 0 citations
These findings establish CAST as a tumor-specific suppressor in CRC and provide a generalizable framework for discovering therapeutic targets from unannotated isoforms.
This study identified TNF, IL6 and other highly connected genes, along with TLR signaling as an enriched pathway in the fibromyalgia-associated gene network, which provides potential molecular targets and pathways for further investigation into the pathophysiology of fibromyalgia.
Mammalian gene switches enable programmable cell behavior. However, current switches on transcriptional and translational layers require de novo RNA and protein synthesis, and secreted outputs must additionally undergo folding, post-translational processing, and intracellular trafficking, imposing delays that limit rap...
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
