The meat of a dinosaur cannot be measured, but the meat of living animals can, and its composition differs with the animal and with the muscle. We asked whether composition can be predicted from traits that a dinosaur also has, and tested this on living animals before applying it. We linked 225 living species, their mu...
S. Yamamoto· Zenodo (CERN European Organi...· 0 citations
Calcium (Ca 2+ ) is a universal second messenger that orchestrates plant growth, development, and stress responses. Plant calcineurin B-like (CBL) proteins sense and relay Ca 2+ ; signals in response to pathogens to activate downstream defense signalling pathways. Early blight disease, caused by the necrotrophic fungal...
Sowrirajan Padmavathy Sowmiyarithika, M. Amrutha, M. Sundar et al.· bioRxiv· 0 citations
This dataset contains processed proteomics data from a comparative LC-MS/MS analysis of extracellular vesicles derived from Rhodobacter sphaeroides under aerobic and anaerobic culture conditions.The deposited files include protein identification and quantitative abundance data, including raw abundance, normalized abund...
Quantitative interpretation of single-molecule localization microscopy (SMLM) data remains limited by fluorophore blinking, incomplete or variable labeling, and the lack of calibration standards that are tunable, synthetic, and compatible with cellular imaging. Here, we evaluate self-assembling protein nanocages as sto...
P. Colosi, S. Hugelier, Melike Lakadamyali· Molecular Biology of the Cel...· 0 citations
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The identification and characterization of multi-stress tolerant Plant Growth-Promoting Bacteria (PGPB) are essential for developing sustainable agricultural strategies to mitigate the effects of abiotic stress factors and intensive agrochemical usage. This study aimed to evaluate the stress tolerance of eleven autocht...
Zh.Zh. Zhaksybek, A. K. Sattarova, S. Abeldenov et al.· Eurasian journal of applied...· 0 citations
Influenza A viruses pose a persistent global health threat due to rapid antigenic drift in the hemagglutinin (HA) globular head. The monomer-monomer head-interface epitope is highly conserved across epidemic H3N2 strains but sterically occluded within the intact HA trimer, rendering it inaccessible to full-size monoclo...
Nolan Yu, Ethan Yu· Zenodo (CERN European Organi...· 0 citations
Microbial metagenomes encode vast catalytic diversity, but recovering enzymes of novel, yet-undescribed functionality typically requires whole-community assembly plus a means of identifying active proteins ab initio. The first step of the task is compute-intensive and misses low-abundance sequences. The second is compl...
R. Prabakaran, Yana Bromberg· bioRxiv (Cold Spring Harbor...· 0 citations
Abstract Hepatitis E virus (HEV) causes over 19 million infections annually, yet the molecular determinants governing its diverse clinical phenotypes and cross-genotype immunity remain incompletely synthesized. The ORF2 capsid protein is the sole structural component of the virion, the primary neutralizing antibody tar...
Shreif A. El-Kafrawy, S. S. Putra, A. Abbas et al.· Journal of General Virology· 0 citations
Molecular protein recognition is governed by discrete algebraic topology rather than continuous geometry or sequence distributions. The core hypotheses state: Topological Novelty: Simply connected complexes ($\beta_{1} = 0$) generate sequences orthogonal to known biologics ($< 20\%$ identity), escaping CDR loop entrapm...
Pediatric and adult cancers diverge profoundly in their molecular architecture, yet whether these differences extend to genome-scale genetic dependencies remains poorly characterized, with prior studies examining single subtypes or individual algorithms rather than a systematic, interpretable comparison. To address t...
Abdulvahap Pınar, Cemil Çolak, A. Arslan· Intelligent Data Analysis· 0 citations
Standing torsion waves in the fabric of spacetime act as resonant cavities for Casimir-E8 vacuum modes, producing quantized angular momentum states whose values are determined by the ratio of 132Hz to φ-scaled E8 root vector frequencies. The Weyl group action on E8 root vectors systematically filters which resonance mo...
Andrew Stewart Caldin· Zenodo (CERN European Organi...· 0 citations
The abstract contains limited description of the BAG due to size limitation. UFM1 (ubiquitin fold modifier 1) is one of the most recent UBLs to be discovered. Protein modification by UFM1 (ufmylation) is essential for the development of different tissues. An increasing body of evidence implicates UFM1 in a wide spectru...
Oded Livnah, Yarden Opatowsky· European Synchrotron Radiati...· 0 citations
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
