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Integrated Transcriptomic Analysis and Machine Learning Identify THY1 as a Key Regulator of Cancer‐Associated Fibroblast Infiltration, Promoting Malignant Progression and Immune Escape in Gastric Cancer

Si-Hui Hou Meng-Zhu Sang Yan Wang Hao-Sheng Que Yi Liu Manman Zhang

Aug 2026 · Journal of Gastroenterology and Hepatology · Vol 41, pp. 2721 - 2738 · 0 citations · 50 references

Medicine

Abstract

Heterogeneity in cancer‐associated fibroblast (CAF) infiltration within the tumor microenvironment is closely associated with gastric cancer progression and immune evasion; however, precise CAF‐related diagnostic markers and actionable therapeutic targets remain scarce.

DOI PubMed Semantic Scholar

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