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protein folding

2,530 papers

#protein folding Open access Sep 2026

Macrophage-derived exosomes carrying RAD50 attenuate oxidative DNA damage and p53-p21-dependent S-phase arrest in spermatogenic cells.

AIMS Occupational heat and blast overpressure impair spermatogenesis, and whether repair capacity supplied from outside the germ cell can lift the resulting block has not been tested. METHODS GC-2 spermatocytes received 1000 shock-wave pulses then 100°C for 40 s, and C57BL/6 mice received a 10% methane blast with int...

Jia-Hua Meng, Zi-Tong Zhang, Ning Li et al. · 0 citations
#protein folding Sep 2026

NIR-Triggered Methylgermanane Nanosheet-Embedded Hydrogels Enable Cascade Dual-Organelle Stress to Potentiate Cancer Immunotherapy.

An accelerated immunomodulatory matrix reservoir (AIMR) integrating methylgermanane nanosheets within an active Ca2 +-crosslinked alginate hydrogel within an active Ca2 +-crosslinked alginate hydrogel provides a dual-organelle stress platform for durable photoimmunotherapy.

Ying-Ying Huang, Yu-Fan Zheng, Qin Zhang et al. · 0 citations
#protein folding Sep 2026

Phosphorus-iron modified biochar reduces soil salinity and enhances carbon sequestration via calcium-sodium exchange and the reverse stimulation of iron-driven functional microbial taxa.

This study hypothesized that phosphorus-iron (P-Fe) modification improves the pore structure and surface chemical properties of biochar, thereby enhancing its adsorption capacity for salt ions and CO2. When incorporated into saline-alkali soil, this modification improves soil fertility and enriches beneficial microbiot...

Yuan-Chun Liang, Xing-Fu Chang, Shi Zhou et al. · 0 citations
#protein folding Sep 2026

The transcription factor CiMYC2 positively regulates terpenoid biosynthesis by activating the expression of CiHMGR and CiTPS4 in Chrysanthemum indicum var. aromaticum.

Chrysanthemum indicum var. aromaticum is a rare aromatic variant, and deciphering its molecular basis could facilitate the breeding of scented chrysanthemums. Here, we introduced its transcription factor CiMYC2 into Chrysanthemum indicum (C. indicum) to investigate the role and mechanism of CiMYC2 in regulating terpeno...

Wen-Jie Gao, Jin-Xiu Han, X. Haotian et al. · 0 citations
#protein folding Sep 2026

Engineering carboxyl methyltransferase for high-efficiency biosynthesis of methyl salicylate in Escherichia coli.

Methyl salicylate (MeSA) is a volatile methylated aromatic ester widely used in agriculture, food, and pharmaceuticals. Microbial biosynthesis offers a sustainable alternative to plant extraction and petrochemical synthesis; however, efficient MeSA production remains limited by the low catalytic efficiency of carboxyl...

Yuan Gao, Shi-Bo Guo, Jun Wu et al. · 0 citations
#protein folding Sep 2026

Strong static magnetic field enhances biomass and high-value lipid production in Chlorella pyrenoidosa via metabolic regulation.

trong static magnetic field (SMF) treatment represents a promising physical strategy for regulating microalgal metabolism. This study investigated the effects of SMF on growth and lipid production in Chlorella pyrenoidosa. Results showed that SMF exposure at 3T for 10 min under photoperiodic conditions was optimal, ach...

Zhen Wang, Li-Ling Fu, Qi-Sheng Tian et al. · 0 citations
#protein folding Open access Sep 2026

Prevalence of antibodies against Tick-Borne Encephalitis Virus in blood donors in the states of Saxony and Berlin/Brandenburg, eastern Germany.

NS1-based serology revealed a markedly underestimated TBEV infection burden and may improve surveillance, identification of emerging risk areas, and targeted vaccination strategies.

P. Girl, Anne B. Schindler, J. Borde et al. · 0 citations
#protein folding Sep 2026

A multidimensional integrated diagnostic strategy using needle sheath flushing solution: combining PGM-based GPC3 protein detection and gene methylation analysis for improved liver cancer diagnosis.

It is demonstrated that NSF-based multidimensional analysis integrating PGM-based GPC3 protein detection and Septin9/RASSF1A methylation profiling provides substantial complementary diagnostic value to conventional pathology, presenting a promising strategy for precision diagnosis of liver cancer.

Li-Sha Wang, Jing Chen, Li-Dan Xing et al. · 0 citations
#protein folding Open access Sep 2026

White and whole wheat flour breads: composition and simultaneous exposure to group B trichothecenes.

BACKGROUND The study aimed to determine the profile of group B trichothecenes (TCTBs), to estimate the daily exposure to them and to evaluate the relationship with the composition of different types of sliced wheat bread. A method for simultaneous determination of the TCTBs (deoxynivalenol (DON), 3-acetyl-deoxynivaleno...

Andressa Cunha Lemos, Verônica Simões de Borba, Milena Da Silva Matsuda Valencia et al. · 0 citations
#protein folding Open access Sep 2026

Tardigrades have a complete condensin II: two divergent CAP-H2 kleisins in three eutardigrade genomes

Condensin II shapes interphase genome architecture: species that lack it tend to fold their chromosomes in a Rabl-like, type-I configuration, while species that have it form chromosome territories (type II). In the study that established this, the tardigrade Hypsibius dujardini (now H. exemplaris) was the only species...

Meow-Ludo Meow-Meow · 0 citations

From tech blogs

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Google DeepMind Blog Sep 30, 2026

Introducing SynthID Bio

Proof of concept for watermarking AI-generated proteins while preserving biological function.

MIT News · Artificial Intelligence Aug 27, 2026

Looking beyond natural sequences

A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.

Google DeepMind Blog Nov 25, 2025

AlphaFold: Five years of impact

Explore how AlphaFold has accelerated science and fueled a global wave of biological discovery.

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