Bard1‐Mediated Regulation of Hnrnpa2b1 Ubiquitination and Protein Stability Contributes to Neuronal Ferroptosis and Cognitive Dysfunction Following Ischemic Stroke
This study investigated the role of Sptbn2 in post‐stroke cognitive impairment (PSCI) and the mechanisms regarding m6A and found that m6A facilitates functional recovery following ischemic stroke.
Abstract
N6‐methyladenosine (m6A) facilitates functional recovery following ischemic stroke (IS). This study investigated the role of Sptbn2 in post‐stroke cognitive impairment (PSCI) and the mechanisms regarding m6A.
This study explored whether intermittent hypoxia modulates injured dorsal root ganglion (DRG) neuron regeneration via lactate‐mediated mechanisms via lactate‐mediated mechanisms.
S. An, Jing-Fei Shi, Jiang Huang et al.· Journal of the peripheral ne...· 0 citations
Itchy E3 ubiquitin‐protein ligase modulates mitochondria, and thrombospondin 1 positively regulates muscle atrophy, but their roles in muscle atrophy are unclear.
Wan Yu, Yan-Teng Wang, Na Li et al.· Acta Physiologica· 0 citations
Microglia‐mediated clearance of amyloid beta (Aβ) is crucial for mitigating Alzheimer's disease (AD) progression, yet the molecular regulators of microglial phagocytosis remain incompletely understood.
Jian Meng, Yong Wang, Jing-Hui Wang et al.· Alzheimer's & Dementia· 0 citations
PUM2 expression increases upon aging and this facilitates the capture/trapping of Mff mRNA, either alone or in association with other RNA-binding proteins (RBPs) in Ribonucleoprotein particles (RNP).
Astrocytes remove extracellular α-synuclein aggregates through p62-dependent autophagy, yet the factors limiting this defense remain unclear. Zhang and colleagues recently identified cholesterol 25-hydroxylase as an inducible negative regulator of p62-mediated clearance. Genetic suppression or a p62-derived decoy pepti...
G. S. Dawe· TIPS - Trends in Pharmacolog...· 0 citations
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