Nucleic acid duplexes, including DNA, RNA, and RNA–DNA hybrid (RDH), undergo structural deformations that are essential for genome replication, transcription, and RNA-mediated regulation. However, quantitative measurements and mechanistic understanding of these deformations remain limited. Here, we probe nucleic acid d...
Despite prolific genomic data from individuals with Alzheimer's disease (AD), translation into treatments has lagged. Here we applied Mendelian randomization to multiple AD genome-wide association studies and functional multiomics datasets to nominate druggable targets, identifying 19 targets for individuals of Europea...
Environmental biotechnology is rapidly reshaping how societies manage pollution, conserve resources, and transition toward sustainable systems. As these technologies advance, they increasingly intersect with complex policy frameworks, regulatory requirements, and ethical considerations. This review examines the evolvin...
Global strawberry (Fragaria x ananassa Duch.) production is about 10,728,811 tons across 436,067 hectares, with Europe contributing 1,194,930 tons from 75,025 hectares (Faostat, 2024). Among European producers, Spain is a major producer with production of 323,540 tons from 7000 hectares (Faostat, 2024). Geographically,...
Patricia López, Ana María Pastrana, Marcus Vinícius Marín et al.· Frontiers in Plant Science· 0 citations
Reach audiences
Advertise in front of researchers, engineers, and readers.
Sepsis is a life-threatening syndrome caused by organ dysfunction resulting from a dysregulated host response to infection, characterized by early hyperinflammation and subsequent immune paralysis or immunosuppression. Macrophage dysregulation is a major driver of this immune imbalance. Tissue-resident macrophages medi...
Huang Wu, Yan Liao, Lingxuan Tang et al.· Molecular Medicine· 0 citations
Species within the genus Rehmannia Bunge ex Link (Orobanchaceae Vent.) are traditional Chinese medicinal plants with important therapeutic and horticultural values. Although bioactive ingredients and related metabolic pathways in Rehmannia species have been extensively studied, their mitochondrial genomes remain poorly...
Modern agriculture targets the improvement of crop yield, nutritional value, and resistance against both biotic and abiotic factors. Genetic modifications are done through mutagenesis techniques. Traditional methods that involved physical or chemical agents lacked specificity and caused unintended mutations at random s...
Mental health is fragile and disorders are highly prevalent arising from complex interactions between genetic, developmental, psychological, social and environmental factors. The key mechanisms underlying resilience, vulnerability factors, brain repair systems, and recovery remain poorly understood, hindering the devel...
S. Safaiyan, M. Schmidt, Annemarie Zimprich et al.· European Archives of Psychia...· 0 citations
Noncoding regulatory elements in the human genome can control gene expression through distinct mechanisms, including acting as enhancers, silencers, or topological elements. However, we lack tools to identify all such classes systematically and quantify their effects on gene expression in an endogenous genomic context....
X. Cai, Michael T. Montgomery, Masahiro Nagano et al.· bioRxiv· 0 citations
In 2025, the world population crossed 8 billion. To serve a huge population, food demand is increasing day by day; however, food security is a matter of concern using traditional agriculture. To fulfil the world’s food demand, genetically modified (GM) crops have been involved in a broad area around the world. To raise...
Pooja Sharma, Soniya Goyal, Diwakar Aggarwal et al.· 0 citations
Human genome sequencing identifies differences in DNA, but the biological meaning of these differences requires further investigation. This extended abstract examines how genome assembly, population comparisons, gene expression analysis and functional experiments contribute to variant interpretation. Four primary studi...
Diyora Muxtoraliyeva· Zenodo (CERN European Organi...· 0 citations
Apolipoprotein C-III (apoC-III) has emerged as a pivotal therapeutic target for lipid-lowering therapies, particularly for hypertriglyceridemia. However, its broader implications in the pathogenesis of atherosclerosis remain to be fully elucidated. ApoC-III is extensively studied for its classical role in modulating li...
Xiawen Yang, Shitao Wang, Wei Huang et al.· Lipids in Health and Disease· 0 citations
Zero-knowledge proofs can verify computing results without rerunning workloads or exposing sensitive data. Magnetar helps bring them into the mainstream with support for standard programming languages, major speed gains, and quantum-resistant security. The post Proof-based general-purpose computing with Magnetar appeared first on Microsoft Research.
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
